产品货号：
Z14494
中文名称：
FAM59A抗体
英文名称：
Anti-FAM59A Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FAM59A Antibody |
| 指标别名 | Gm944,FAM59A,C18orf11,GRB2-associated and regulator of MAPK protein,GRB2-associated and regulator of MAPK1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | FAM59A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FAM59A antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FAM59A.The immunogen is located within amino acids 630 - 680 of FAM59A. |
| 计算分子量 | 97kDa |
| 成分 | FAM59A Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FAM59A Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | FAM59A,also known as GAREM,was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli.FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated,and this phosphorylation is needed for the binding of Grb2,an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus.ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells,and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar,suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells. |
| Uniprot ID | Q9H706 |
| 基因名全称 | Family with sequence similarity 59,member A |
| 蛋白名全称 | Family with sequence similarity 59,member A |
| 推荐稀释比 | FAM59A antibody can be used for detection of FAM59A by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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